For 50% of men over the age of sixty, acquiring a Benign Prostatic Hyperplasia (BPH) is a reality they will face. The enlarged prostate that accompanies BPH means a block of urine flow, resulting in severe bladder complications and extreme discomfort for many men.

While different surgical options are available, most prove rife with complications and come with significant recovery times and re-treatment rate; transurethral resection of the prostate (TURP) and open prostatectomies can lead to surgical site infections, salt imbalances, improper fluid absorption and, most troublingly, bleeding during surgery to the point of needing a transfusion and prolonged hospitalisation post-op.

In these cases, surgeons are required to ensure proper measures are taken throughout the surgery, adding unnecessary time to procedures and taking surgeons attention away from the core concern. Holmium Laser Enucleation of the Prostate (HoLEP) presents a safe and highly effective solution to BPH treatment and has long been considered the Gold-Standard treatment. Specifically, Lumenis’ MOSES™ Pulse 120H technology represents a major paradigm shift in BPH treatments, transforming the clinically validated gold-standard HoLEP, into an outpatient procedure with same day discharge, catheter-free.1-5

Because it simultaneously cuts adenoma and cauterises blood vessels, MOSES provides 15% faster prostate enucleation and 40% faster hemostasis, which significantly reduce overall surgery time, anaesthesia use and bleeding1. This results in shorter length of hospital stay, better surgical outcomes and higher patient satisfaction, and translates into thousands of dollars of contribution per procedure to the healthcare provider’s profitability.6

Working with the Lumenis’ MOSES Pulse 120H laser system improves intraoperative vision and provides better fibre stability and a cleaner dissection of the capsular plane, increasing efficiency and maximising results.6,7 The uniquely optimised MOSES Holmium laser bubble for BPH has contributed to a better safety profile of HoLEP whilst minimising the chance of patients requiring transfusions during surgery, as well as decreasing the necessary hospital time needed for surgery.8,9

“I’ve used the MOSES technology during stones and BPH procedures for several years because it is so efficient”, says Dr. Amy E. Krambeck, Professor of Urology at Indiana University School of Medicine in Indianapolis, USA. “MOSES for HoLEP enucleates tissue even faster and stops bleeding very quickly, which is important for visibility, postoperative recovery and the surgeon’s learning curve. It allowed me to change my entire practice and patients have been very happy to go home the same day without a catheter. This transformation is even more important now that COVID-19 makes patients put off essential care, while our hospitals move to free up inpatient beds for acute cases. MOSES helps make that possible.”

Learn more about how MOSES technology is revolutionising urology care here.



  1. Cornu JN et al. A Systematic Review and Meta-analysis of Functional Outcomes and Complications Following Transurethral Procedures for Lower Urinary Tract Symptoms Resulting from Benign Prostatic Obstruction: An Update. Eur Urol. 2015;67:1066-96.
  2. Zhong J et al. A Systematic Review and Meta-analysis of Efficacy and Safety Following Holmium Laser Enucleation of Prostate and Transurethral Resection of Prostate for Benign Prostatic Hyperplasia. Urology. 2019;131:14-20.
  3. Jhanwar A et al. Outcomes of Transurethral Resection and Holmium Laser Enucleation in More than 60 g of Prostate: A Prospective Randomized Study. Urol Ann. 2017;9:45-50.
  4. Elsahal AM et al. Holmium Laser Enucleation of the Prostate for Treatment for Large‑sized Benign Prostate Hyperplasia; Is It a Realistic Endourologic Alternative in Developing Country? World J Urol. 2016;34:399-405.
  5. Fayad AS. Holmium Laser Enucleation of the Prostate versus Bipolar Resection of the Prostate; A Prospective Randomized Study. “Pros and Cons”. Urology. 2015;86:1037-41.
  6. Large T et al. Comparative Study of Holmium Laser Enucleation of the Prostate With MOSES Enabled Pulsed Laser Modulation. Urology. 2020;136:196-201.
  7. Y Hussein MI et al. MOSES, A New Technology for HoLEP. J Urol. 2019:201(4S).e164.
  8. Agarwal DK et al. Current Era Holmium Laser Enucleation of the Prostate Is a Safe, Reliable Day Surgery. J Urol. 2020:203(4S).e488.
  9. Meskawi M et al. Holmium Laser Enucleation of the Prostate Using Moses Technology in Treating Benign Prostate Hyperplasia. J Urol. 2019:201(4S).e167.

*Risk information and laser safety label are available at Lumenis website, operator’s manual and brochure.

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